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Organoids Are Limited in Modeling the Colon Adenoma–Carcinoma Sequence

The colon adenoma–carcinoma sequence is a multistep genomic-altering process that occurs during colorectal cancer (CRC) carcinogenesis. Organoids are now commonly used to model both non-cancerous and cancerous tissue. This study aims to investigate how well organoids mimic tissues in the adenoma–car...

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Detalles Bibliográficos
Autores principales: Tokumaru, Yoshihisa, Oshi, Masanori, Patel, Ankit, Tian, Wanqing, Yan, Li, Matsuhashi, Nobuhisa, Futamura, Manabu, Yoshida, Kazuhiro, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996178/
https://www.ncbi.nlm.nih.gov/pubmed/33668713
http://dx.doi.org/10.3390/cells10030488