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L-Alanine Prototrophic Suppressors Emerge from L-Alanine Auxotroph through Stress-Induced Mutagenesis in Escherichia coli

In Escherichia coli, L-alanine is synthesized by three isozymes: YfbQ, YfdZ, and AvtA. When an E. coli L-alanine auxotrophic isogenic mutant lacking the three isozymes was grown on L-alanine-deficient minimal agar medium, L-alanine prototrophic mutants emerged considerably more frequently than by sp...

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Detalles Bibliográficos
Autores principales: Mishima, Harutaka, Watanabe, Hirokazu, Uchigasaki, Kei, Shimoda, So, Seki, Shota, Kumagai, Toshitaka, Nochi, Tomonori, Ando, Tasuke, Yoneyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996224/
https://www.ncbi.nlm.nih.gov/pubmed/33668720
http://dx.doi.org/10.3390/microorganisms9030472