Lyophilization Serves as an Effective Strategy for Drug Development of the α9α10 Nicotinic Acetylcholine Receptor Antagonist α-Conotoxin GeXIVA[1,2]

α-Conotoxin GeXIVA[1,2] is a highly potent and selective antagonist of the α9α10 nicotinic acetylcholine receptor (nAChR) subtype. It has the advantages of strong efficacy, no tolerance, and no effect on motor function, which has been expected help patients with neuropathic pain. However, drug devel...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhiguo, Han, Xiaolu, Hong, Xiaoxuan, Li, Xianfu, Gao, Jing, Zhang, Hui, Zheng, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996264/
https://www.ncbi.nlm.nih.gov/pubmed/33668830
http://dx.doi.org/10.3390/md19030121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996264/
https://www.ncbi.nlm.nih.gov/pubmed/33668830
http://dx.doi.org/10.3390/md19030121

Ejemplares similares