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A Novel One-Pot Enzyme Cascade for the Biosynthesis of Cladribine Triphosphate
Cladribine triphosphate is the active compound of the anti-cancer and multiple sclerosis drug Mavenclad (cladribine). Biosynthesis of such non-natural deoxyribonucleotides is challenging but important in order to study the pharmaceutical modes of action. In this study, we developed a novel one-pot e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996316/ https://www.ncbi.nlm.nih.gov/pubmed/33668847 http://dx.doi.org/10.3390/biom11030346 |