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What Is the Best Predictor of Phenobarbital Pharmacokinetics to Use for Initial Dosing in Neonates?

Phenobarbital is a first-line treatment of various seizure types in newborns. Dosage individualization maximizing the proportion of patients with drug levels in therapeutic range or sufficient treatment response is still challenging. The aim of this review was to summarize the available evidence on...

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Detalles Bibliográficos
Autores principales: Šíma, Martin, Michaličková, Danica, Slanař, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996486/
https://www.ncbi.nlm.nih.gov/pubmed/33668911
http://dx.doi.org/10.3390/pharmaceutics13030301