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Consideration of Sex as a Biological Variable in the Development of Doxorubicin Myotoxicity and the Efficacy of Exercise as a Therapeutic Intervention

Doxorubicin (DOX) is an anthracycline antibiotic used to treat a wide variety of hematological and solid tumor cancers. While DOX is highly effective at reducing tumor burden, its clinical use is limited by the development of adverse effects to both cardiac and skeletal muscle. The detrimental effec...

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Detalles Bibliográficos
Autores principales: Montalvo, Ryan N., Doerr, Vivian, Nguyen, Branden L., Kelley, Rachel C., Smuder, Ashley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996538/
https://www.ncbi.nlm.nih.gov/pubmed/33669040
http://dx.doi.org/10.3390/antiox10030343