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Small Molecule CCR4 Antagonists Protect Mice from Aspergillus Infection and Allergy
The ability to regulate the recruitment of immune cells makes chemokines and their receptors attractive drug targets in many inflammatory diseases. Based on its preferential expression on T helper type 2 (Th2) cells, C-C chemokine receptor type 4 (CCR4) has been widely studied in the context of alle...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996545/ https://www.ncbi.nlm.nih.gov/pubmed/33669094 http://dx.doi.org/10.3390/biom11030351 |