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Small Molecule CCR4 Antagonists Protect Mice from Aspergillus Infection and Allergy

The ability to regulate the recruitment of immune cells makes chemokines and their receptors attractive drug targets in many inflammatory diseases. Based on its preferential expression on T helper type 2 (Th2) cells, C-C chemokine receptor type 4 (CCR4) has been widely studied in the context of alle...

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Detalles Bibliográficos
Autores principales: Bozza, Silvia, Iannitti, Rossana Giulietta, Pariano, Marilena, Renga, Giorgia, Costantini, Claudio, Romani, Luigina, Bayry, Jagadeesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996545/
https://www.ncbi.nlm.nih.gov/pubmed/33669094
http://dx.doi.org/10.3390/biom11030351

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