Synthesis, Cytotoxicity and Anti-Proliferative Activity against AGS Cells of New 3(2H)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker

Novel twenty-three 3(2H)-pyridazinone derivatives were designed and synthesized based on the chemical requirements related to the anti-proliferative effects previously demonstrated within this scaffold. The introduction of a piperazinyl linker between the pyridazinone nucleus and the additional (un)...

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Detalles Bibliográficos
Autores principales: Alagöz, Mehmet Abdullah, Özdemir, Zeynep, Uysal, Mehtap, Carradori, Simone, Gallorini, Marialucia, Ricci, Alessia, Zara, Susi, Mathew, Bijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996573/
https://www.ncbi.nlm.nih.gov/pubmed/33668893
http://dx.doi.org/10.3390/ph14030183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996573/
https://www.ncbi.nlm.nih.gov/pubmed/33668893
http://dx.doi.org/10.3390/ph14030183

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