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Synthesis, Cytotoxicity and Anti-Proliferative Activity against AGS Cells of New 3(2H)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker
Novel twenty-three 3(2H)-pyridazinone derivatives were designed and synthesized based on the chemical requirements related to the anti-proliferative effects previously demonstrated within this scaffold. The introduction of a piperazinyl linker between the pyridazinone nucleus and the additional (un)...
Autores principales: | Alagöz, Mehmet Abdullah, Özdemir, Zeynep, Uysal, Mehtap, Carradori, Simone, Gallorini, Marialucia, Ricci, Alessia, Zara, Susi, Mathew, Bijo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996573/ https://www.ncbi.nlm.nih.gov/pubmed/33668893 http://dx.doi.org/10.3390/ph14030183 |
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