p62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)–Curcumin Complex

The hyperactivation of nuclear factor erythroid 2 p45-related factor 2 (NRF2), frequently found in many tumor types, can be responsible for cancer resistance to therapies and poor patient prognosis. Curcumin has been shown to activate NRF2 that has cytotprotective or protumorigenic roles according t...

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Detalles Bibliográficos
Autores principales: Garufi, Alessia, Giorno, Eugenia, Gilardini Montani, Maria Saveria, Pistritto, Giuseppa, Crispini, Alessandra, Cirone, Mara, D’Orazi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996602/
https://www.ncbi.nlm.nih.gov/pubmed/33669070
http://dx.doi.org/10.3390/biom11030348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996602/
https://www.ncbi.nlm.nih.gov/pubmed/33669070
http://dx.doi.org/10.3390/biom11030348

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