Nrf2 Signaling Pathway in Chemoprotection and Doxorubicin Resistance: Potential Application in Drug Discovery

Doxorubicin (DOX) is extensively applied in cancer therapy due to its efficacy in suppressing cancer progression and inducing apoptosis. After its discovery, this chemotherapeutic agent has been frequently used for cancer therapy, leading to chemoresistance. Due to dose-dependent toxicity, high conc...

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Detalles Bibliográficos
Autores principales: Mirzaei, Sepideh, Zarrabi, Ali, Hashemi, Farid, Zabolian, Amirhossein, Saleki, Hossein, Azami, Negar, Hamzehlou, Soodeh, Farahani, Mahdi Vasheghani, Hushmandi, Kiavash, Ashrafizadeh, Milad, Khan, Haroon, Kumar, Alan Prem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996755/
https://www.ncbi.nlm.nih.gov/pubmed/33652780
http://dx.doi.org/10.3390/antiox10030349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996755/
https://www.ncbi.nlm.nih.gov/pubmed/33652780
http://dx.doi.org/10.3390/antiox10030349

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