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Functional Dissection of the Dominant Role of CD55 in Protecting Vesicular Stomatitis Virus against Complement-Mediated Neutralization

The human complement system is an important part of the innate immune system. Its effector pathways largely mediate virus neutralization. Vesicular stomatitis virus (VSV) activates the classical pathway of the complement, leading to virus neutralization by lysis. Two host-derived membrane-associated...

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Detalles Bibliográficos
Autores principales: Asok Kumar, Nisha, Muraleedharan Suma, Sreenath, Kunnakkadan, Umerali, Nag, Joydeep, Koolaparambil Mukesh, Reshma, Lyles, Douglas S., Johnson, John Bernet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996768/
https://www.ncbi.nlm.nih.gov/pubmed/33652918
http://dx.doi.org/10.3390/v13030373