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Statistical Evidence for a Helical Nascent Chain

We investigate the hypothesis that protein folding is a kinetic, non-equilibrium process, in which the structure of the nascent chain is crucial. We compare actual amino acid frequencies in loops, [Formula: see text]-helices and [Formula: see text]-sheets with the frequencies that would arise in the...

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Detalles Bibliográficos
Autores principales: Cruzeiro, Leonor, Gill, Andrew C., Eilbeck, J. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996779/
https://www.ncbi.nlm.nih.gov/pubmed/33652806
http://dx.doi.org/10.3390/biom11030357