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Pitfalls in the Serological Diagnosis of Primary Human Cytomegalovirus Infection in Pregnancy Due to Different Kinetics of IgM Clearance and IgG Avidity Index Maturation

Primary infection occurs when seronegative women are infected by human cytomegalovirus (HCMV). Diagnosis of primary infection is based on the following: antibody seroconversion, presence of IgM and low IgG avidity index (AI), and presence of DNAemia. The kinetics of HCMV-specific IgM antibody and ma...

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Detalles Bibliográficos
Autores principales: Sarasini, Antonella, Arossa, Alessia, Zavattoni, Maurizio, Fornara, Chiara, Lilleri, Daniele, Spinillo, Arsenio, Baldanti, Fausto, Furione, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996894/
https://www.ncbi.nlm.nih.gov/pubmed/33652709
http://dx.doi.org/10.3390/diagnostics11030396