SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation

Viral infection-induced activation of inflammasome complexes has both positive and negative effects on the host. Proper activation of inflammasome complexes induces down-stream effector mechanisms that inhibit viral replication and promote viral clearance, whereas dysregulated activation has detrime...

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Detalles Bibliográficos
Autores principales: Kim, Na-Eun, Kim, Dae-Kyum, Song, Yoon-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996899/
https://www.ncbi.nlm.nih.gov/pubmed/33652815
http://dx.doi.org/10.3390/microorganisms9030494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996899/
https://www.ncbi.nlm.nih.gov/pubmed/33652815
http://dx.doi.org/10.3390/microorganisms9030494

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