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SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation
Viral infection-induced activation of inflammasome complexes has both positive and negative effects on the host. Proper activation of inflammasome complexes induces down-stream effector mechanisms that inhibit viral replication and promote viral clearance, whereas dysregulated activation has detrime...
Autores principales: | Kim, Na-Eun, Kim, Dae-Kyum, Song, Yoon-Jae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996899/ https://www.ncbi.nlm.nih.gov/pubmed/33652815 http://dx.doi.org/10.3390/microorganisms9030494 |
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