Oceanapiside, a Marine Natural Product, Targets the Sphingolipid Pathway of Fluconazole-Resistant Candida glabrata

Oceanapiside (OPS), a marine natural product with a novel bifunctional sphingolipid structure, is fungicidal against fluconazole-resistant Candida glabrata at 10 μg/mL (15.4 μM). The fungicidal effect was observed at 3 to 4 h after exposure to cells. Cytological and morphological studies revealed th...

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Detalles Bibliográficos
Autores principales: Dalisay, Doralyn S., Rogers, Evan W., Molinski, Tadeusz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996939/
https://www.ncbi.nlm.nih.gov/pubmed/33652774
http://dx.doi.org/10.3390/md19030126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996939/
https://www.ncbi.nlm.nih.gov/pubmed/33652774
http://dx.doi.org/10.3390/md19030126

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