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Induction of interferon-β and interferon signaling by TRAIL and Smac mimetics via caspase-8 in breast cancer cells

Breast cancer prognosis is frequently good but a substantial number of patients suffer from relapse. The death receptor ligand TRAIL can in combination with Smac mimetics induce apoptosis in some luminal-like ER-positive breast cancer cell lines, such as CAMA-1, but not in MCF-7 cells. Here we show...

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Detalles Bibliográficos
Autores principales: Granqvist, Victoria, Holmgren, Christian, Larsson, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996988/
https://www.ncbi.nlm.nih.gov/pubmed/33770100
http://dx.doi.org/10.1371/journal.pone.0248175