The diagnostic accuracy of digital PCR, ARMS and NGS for detecting KRAS mutation in cell-free DNA of patients with colorectal cancer: A systematic review and meta-analysis

INTRODUCTION: Before anti-EGFR therapy is given to patients with colorectal cancer, it is required to determine KRAS mutation status in tumor. When tumor tissue is not available, cell-free DNA (liquid biopsy) is commonly used as an alternative. Due to the low abundance of tumor-derived DNA in cell-f...

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Detalles Bibliográficos
Autores principales: Ye, Peng, Cai, Peiling, Xie, Jing, Wei, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997033/
https://www.ncbi.nlm.nih.gov/pubmed/33770081
http://dx.doi.org/10.1371/journal.pone.0248775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997033/
https://www.ncbi.nlm.nih.gov/pubmed/33770081
http://dx.doi.org/10.1371/journal.pone.0248775

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