Mycobacterium leprae promotes triacylglycerol de novo synthesis through induction of GPAT3 expression in human premonocytic THP-1 cells

Mycobacterium leprae (M. leprae) is the etiological agent of leprosy, and the skin lesions of lepromatous leprosy are filled with numerous foamy or xanthomatous histiocytes that are parasitized by M. leprae. Lipids are an important nutrient for the intracellular survival of M. leprae. In this study,...

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Detalles Bibliográficos
Autores principales: Tanigawa, Kazunari, Hayashi, Yasuhiro, Hama, Kotaro, Yamashita, Atsushi, Yokoyama, Kazuaki, Luo, Yuqian, Kawashima, Akira, Maeda, Yumi, Nakamura, Yasuhiro, Harada, Ayako, Kiriya, Mitsuo, Karasawa, Ken, Suzuki, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997041/
https://www.ncbi.nlm.nih.gov/pubmed/33770127
http://dx.doi.org/10.1371/journal.pone.0249184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997041/
https://www.ncbi.nlm.nih.gov/pubmed/33770127
http://dx.doi.org/10.1371/journal.pone.0249184

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