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A unified framework for inferring the multi-scale organization of chromatin domains from Hi-C

Chromosomes are giant chain molecules organized into an ensemble of three-dimensional structures characterized with its genomic state and the corresponding biological functions. Despite the strong cell-to-cell heterogeneity, the cell-type specific pattern demonstrated in high-throughput chromosome c...

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Detalles Bibliográficos
Autores principales: Bak, Ji Hyun, Kim, Min Hyeok, Liu, Lei, Hyeon, Changbong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997044/
https://www.ncbi.nlm.nih.gov/pubmed/33724986
http://dx.doi.org/10.1371/journal.pcbi.1008834