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A unified framework for inferring the multi-scale organization of chromatin domains from Hi-C
Chromosomes are giant chain molecules organized into an ensemble of three-dimensional structures characterized with its genomic state and the corresponding biological functions. Despite the strong cell-to-cell heterogeneity, the cell-type specific pattern demonstrated in high-throughput chromosome c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997044/ https://www.ncbi.nlm.nih.gov/pubmed/33724986 http://dx.doi.org/10.1371/journal.pcbi.1008834 |