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In Silico Plasma Protein Binding Studies of Selected Group of Drugs Using TLC and HPLC Retention Data

Plasma protein binding is an important determinant of the pharmacokinetic properties of chemical compounds in living organisms. The aim of the present study was to determine the index of protein binding affinity based on chromatographic experiments. The question is which chromatographic environment...

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Detalles Bibliográficos
Autores principales: Wanat, Karolina, Żydek, Grażyna, Hekner, Adam, Brzezińska, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997166/
https://www.ncbi.nlm.nih.gov/pubmed/33671019
http://dx.doi.org/10.3390/ph14030202