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In Silico Plasma Protein Binding Studies of Selected Group of Drugs Using TLC and HPLC Retention Data
Plasma protein binding is an important determinant of the pharmacokinetic properties of chemical compounds in living organisms. The aim of the present study was to determine the index of protein binding affinity based on chromatographic experiments. The question is which chromatographic environment...
Autores principales: | Wanat, Karolina, Żydek, Grażyna, Hekner, Adam, Brzezińska, Elżbieta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997166/ https://www.ncbi.nlm.nih.gov/pubmed/33671019 http://dx.doi.org/10.3390/ph14030202 |
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