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Synthesis, Biological Activity and In Silico Pharmacokinetic Prediction of a New 2-Thioxo-Imidazoldidin-4-One of Primaquine

The discovery of novel antiparasitic drugs for neglected tropical diseases (NTDs) constitutes a global urgency and requires a range of innovative strategies to ensure a sustainable pipeline of lead compounds. Thus far, primaquine (PQ) is the only transmission-blocking antimalarial that is clinically...

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Detalles Bibliográficos
Autores principales: Pereira, Mariana, Caljon, Guy, Gouveia, Maria João, Maes, Louis, Vale, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997226/
https://www.ncbi.nlm.nih.gov/pubmed/33673562
http://dx.doi.org/10.3390/ph14030196