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Synthesis, Biological Activity and In Silico Pharmacokinetic Prediction of a New 2-Thioxo-Imidazoldidin-4-One of Primaquine
The discovery of novel antiparasitic drugs for neglected tropical diseases (NTDs) constitutes a global urgency and requires a range of innovative strategies to ensure a sustainable pipeline of lead compounds. Thus far, primaquine (PQ) is the only transmission-blocking antimalarial that is clinically...
Autores principales: | Pereira, Mariana, Caljon, Guy, Gouveia, Maria João, Maes, Louis, Vale, Nuno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997226/ https://www.ncbi.nlm.nih.gov/pubmed/33673562 http://dx.doi.org/10.3390/ph14030196 |
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