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TIGIT/CD226 Axis Regulates Anti-Tumor Immunity

Tumors escape immune surveillance by inducing various immunosuppressive pathways, including the activation of inhibitory receptors on tumor-infiltrating T cells. While monoclonal antibodies (mAbs) blocking programmed cell death 1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic T lymphocyte-...

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Detalles Bibliográficos
Autores principales: Yeo, Jinah, Ko, Minkyung, Lee, Dong-Hee, Park, Yoon, Jin, Hyung-seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997242/
https://www.ncbi.nlm.nih.gov/pubmed/33670993
http://dx.doi.org/10.3390/ph14030200