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Extracellular Vesicle miR-200c Enhances Gefitinib Sensitivity in Heterogeneous EGFR-Mutant NSCLC

Intratumoral heterogeneity in epidermal growth factor receptor (EGFR)-mutant mutant non-small-cell lung cancer (NSCLC) explains the mixed responses to EGFR-tyrosine kinase inhibitors (TKIs). However, some studies showed tumors with low abundances of EGFR mutation still respond to EGFR-TKI, and the m...

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Detalles Bibliográficos
Autores principales: Lin, Chien-Chung, Wu, Chin-You, Tseng, Joseph Ta-Chien, Hung, Chun-Hua, Wu, Shang-Yin, Huang, Yu-Ting, Chang, Wei-Yuan, Su, Po-Lan, Su, Wu-Chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997352/
https://www.ncbi.nlm.nih.gov/pubmed/33671000
http://dx.doi.org/10.3390/biomedicines9030243