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Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation
Heme oxygenase catalyzes the rate-limiting step in heme degradation in order to generate biliverdin, carbon monoxide (CO), and iron. The inducible form of the enzyme, heme oxygenase-1 (HO-1), exerts a central role in cellular protection. The substrate, heme, is a potent pro-oxidant that can accelera...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997353/ https://www.ncbi.nlm.nih.gov/pubmed/33671004 http://dx.doi.org/10.3390/cells10030515 |