Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABA(B) Receptor: A Path-Metadynamics Study

[Image: see text] γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the central nervous system (CNS). Dysfunctional GABAergic neurotransmission is associated with numerous neurological and neuropsychiatric disorders. The GABA(B) receptor (GABA(B)-R) is a heterodimeric class C G p...

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Detalles Bibliográficos
Autores principales: Evenseth, Linn S. M., Ocello, Riccardo, Gabrielsen, Mari, Masetti, Matteo, Recanatini, Maurizio, Sylte, Ingebrigt, Cavalli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997371/
https://www.ncbi.nlm.nih.gov/pubmed/32233432
http://dx.doi.org/10.1021/acs.jcim.0c00163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997371/
https://www.ncbi.nlm.nih.gov/pubmed/32233432
http://dx.doi.org/10.1021/acs.jcim.0c00163

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