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Innovative IgG Biomarkers Based on Phage Display Microbial Amyloid Mimotope for State and Stage Diagnosis in Alzheimer’s Disease

[Image: see text] An innovative approach to identify new conformational antigens of Aβ(1–42) recognized by IgG autoantibodies as biomarkers of state and stage in Alzheimer’s disease (AD) patients is described. In particular, through the use of bioinformatics modeling, conformational similarities bet...

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Detalles Bibliográficos
Autores principales: De Plano, Laura M., Carnazza, Santina, Franco, Domenico, Rizzo, Maria Giovanna, Conoci, Sabrina, Petralia, Salvatore, Nicoletti, Alessandra, Zappia, Mario, Campolo, Michela, Esposito, Emanuela, Cuzzocrea, Salvatore, Guglielmino, Salvatore P. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997372/
https://www.ncbi.nlm.nih.gov/pubmed/32176482
http://dx.doi.org/10.1021/acschemneuro.9b00549