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Integrated Proteomic and Phosphoproteomics Analysis of DKK3 Signaling Reveals Activated Kinase in the Most Aggressive Gallbladder Cancer

DKK3 is a secreted protein, which belongs to a family of Wnt antagonists and acts as a potential tumor suppressor in gallbladder cancer. To further understand its tumor suppressor functions, we overexpressed DKK3 in 3 GBC cell lines. We have employed high-resolution mass spectrometry and tandem mass...

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Detalles Bibliográficos
Autores principales: Gondkar, Kirti, Sathe, Gajanan, Joshi, Neha, Nair, Bipin, Pandey, Akhilesh, Kumar, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997438/
https://www.ncbi.nlm.nih.gov/pubmed/33670899
http://dx.doi.org/10.3390/cells10030511