Cargando…

Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology

We developed genetic-epigenetic tissue mapping (GETMap) to determine the tissue composition of plasma DNA carrying genetic variants not present in the constitutional genome through comparing their methylation profiles with relevant tissues. We validated this approach by showing that, in pregnant wom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gai, Wanxia, Zhou, Ze, Agbor-Enoh, Sean, Fan, Xiaodan, Lian, Sheng, Jiang, Peiyong, Cheng, Suk Hang, Wong, John, Chan, Stephen L, Jang, Moon Kyoo, Yang, Yanqin, Liang, Raymond HS, Chan, Wai Kong, Ma, Edmond SK, Leung, Tak Y, Chiu, Rossa WK, Valantine, Hannah, Chan, KC Allen, Lo, YM Dennis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997656/ https://www.ncbi.nlm.nih.gov/pubmed/33752803 http://dx.doi.org/10.7554/eLife.64356

Ejemplares similares

Enrichment of fetal and maternal long cell‐free DNA fragments from maternal plasma following DNA repair
por: Vong, Joaquim S.L., et al.
Publicado: (2019)

Noninvasive Prenatal Diagnosis of Fetal Trisomy 21 by Allelic Ratio Analysis Using Targeted Massively Parallel Sequencing of Maternal Plasma DNA
por: Liao, Gary J. W., et al.
Publicado: (2012)

Detection and characterization of jagged ends of double-stranded DNA in plasma
por: Jiang, Peiyong, et al.
Publicado: (2020)

Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma
por: Yu, Stephanie C. Y., et al.
Publicado: (2013)

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin
por: Sun, Kun, et al.
Publicado: (2019)

Nuclease deficiencies alter plasma cell-free DNA methylation profiles
por: Han, Diana S.C., et al.
Publicado: (2021)

Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing
por: Sun, Kun, et al.
Publicado: (2018)

Automated extraction protocol for quantification of SARS-Coronavirus RNA in serum: an evaluation study
por: Chiu, Rossa WK, et al.
Publicado: (2006)

A simple and rapid approach for screening of SARS-coronavirus genotypes: an evaluation study
por: Chung, Grace TY, et al.
Publicado: (2005)

Effects of nucleases on cell-free extrachromosomal circular DNA
por: Sin, Sarah T.K., et al.
Publicado: (2022)

The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB
por: Han, Diana S.C., et al.
Publicado: (2020)

Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study
por: Chan, KC Allen, et al.
Publicado: (2005)

2018 ATS BEAR Cage Winning Proposal: Cell-Free DNA to Improve Lung Transplant Outcomes
por: Agbor-Enoh, Sean
Publicado: (2019)

Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasma
por: Burnham, Philip, et al.
Publicado: (2016)

Cell-Free DNA Tissue Damage Mapping in Transplant Patients Infected with COVID-19
por: Andargie, T.E., et al.
Publicado: (2021)

Donor-Derived Cell-Free DNA for Acute Rejection Monitoring in Heart and Lung Transplantation
por: Keller, Michael, et al.
Publicado: (2021)

Tracing SARS-Coronavirus Variant with Large Genomic Deletion
por: Chiu, Rossa W.K., et al.
Publicado: (2005)

High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-End Massively Parallel Sequencing
por: Tsui, Nancy B. Y., et al.
Publicado: (2012)

Identification and characterization of extrachromosomal circular DNA in maternal plasma
por: Sin, Sarah T. K., et al.
Publicado: (2020)

Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients
por: Lee, Nelson, et al.
Publicado: (2004)

Cell-free chromatin immunoprecipitation to detect molecular pathways in heart transplantation
por: Jang, Moon Kyoo, et al.
Publicado: (2023)

FetalQuant(SD): accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA
por: Jiang, Peiyong, et al.
Publicado: (2016)

Prenatal Diagnosis of Fetuses With Increased Nuchal Translucency by Genome Sequencing Analysis
por: Choy, Kwong Wai, et al.
Publicado: (2019)

Genome-wide detection of cytosine methylation by single molecule real-time sequencing
por: Tse, O. Y. Olivia, et al.
Publicado: (2021)

Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma
por: Lam, W. K. Jacky, et al.
Publicado: (2018)

Effects of tai chi qigong on psychosocial well-being among hidden elderly, using elderly neighborhood volunteer approach: a pilot randomized controlled trial
por: Chan, Aileen WK, et al.
Publicado: (2017)

Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing
por: Chen, Eric Z., et al.
Publicado: (2011)

Cell‐free fetal DNA coming in all sizes and shapes
por: Chiu, Rossa W. K., et al.
Publicado: (2021)

Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies
por: Hudecova, Irena, et al.
Publicado: (2014)

Epigenetic analysis of cell-free DNA by fragmentomic profiling
por: Zhou, Qing, et al.
Publicado: (2022)

Use of Social Network Sites for Communication Among Health Professionals: Systematic Review
por: Chan, Windy SY, et al.
Publicado: (2018)

Facebook as a Novel Tool for Continuous Professional Education on Dementia: Pilot Randomized Controlled Trial
por: Chan, Windy SY, et al.
Publicado: (2020)

Authors’ Reply to: Comment on “Facebook as a Novel Tool for Continuous Professional Education on Dementia: Pilot Randomized Controlled Trial”
por: Chan, Windy SY, et al.
Publicado: (2020)

Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma
por: Yu, Stephanie C. Y., et al.
Publicado: (2021)

The SIRPα–CD47 immune checkpoint in NK cells
por: Deuse, Tobias, et al.
Publicado: (2021)

Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs
por: Zhou, Ze, et al.
Publicado: (2023)

Draft Genome Sequence of Helicobacter cinaedi, Compiled by Direct Whole-Genome Sequencing of a Blood Culture-Positive Isolate in Hong Kong
por: Chan, Wai-Sing, et al.
Publicado: (2018)

Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome
por: Tsui, Dana W. Y., et al.
Publicado: (2010)

Prenatal sonography of placental abscess and prolonged antibiotic treatment for Serratia marcescens bacteremia
por: Mak, Annisa Shui Lam, et al.
Publicado: (2018)

Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction
por: Chan, Rebecca W.Y., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8m73pcmevb6i85f951boh3rufq