A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch

Optogenetics enables genome manipulations with high spatiotemporal resolution, opening exciting possibilities for fundamental and applied biological research. Here, we report the development of LiCre, a novel light-inducible Cre recombinase. LiCre is made of a single flavin-containing protein compri...

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Detalles Bibliográficos
Autores principales: Duplus-Bottin, Hélène, Spichty, Martin, Triqueneaux, Gérard, Place, Christophe, Mangeot, Philippe Emmanuel, Ohlmann, Théophile, Vittoz, Franck, Yvert, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997657/
https://www.ncbi.nlm.nih.gov/pubmed/33620312
http://dx.doi.org/10.7554/eLife.61268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997657/
https://www.ncbi.nlm.nih.gov/pubmed/33620312
http://dx.doi.org/10.7554/eLife.61268

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