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A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch
Optogenetics enables genome manipulations with high spatiotemporal resolution, opening exciting possibilities for fundamental and applied biological research. Here, we report the development of LiCre, a novel light-inducible Cre recombinase. LiCre is made of a single flavin-containing protein compri...
Autores principales: | Duplus-Bottin, Hélène, Spichty, Martin, Triqueneaux, Gérard, Place, Christophe, Mangeot, Philippe Emmanuel, Ohlmann, Théophile, Vittoz, Franck, Yvert, Gaël |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997657/ https://www.ncbi.nlm.nih.gov/pubmed/33620312 http://dx.doi.org/10.7554/eLife.61268 |
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