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Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor

Kainate receptors (KARs) are L-glutamate-gated ion channels that regulate synaptic transmission and modulate neuronal circuits. KARs have strict assembly rules and primarily function as heteromeric receptors in the brain. A longstanding question is how KAR heteromer subunits organize and coordinate...

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Detalles Bibliográficos
Autores principales: Khanra, Nandish, Brown, Patricia MGE, Perozzo, Amanda M, Bowie, Derek, Meyerson, Joel R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997659/
https://www.ncbi.nlm.nih.gov/pubmed/33724189
http://dx.doi.org/10.7554/eLife.66097