Cargando…
Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
Kainate receptors (KARs) are L-glutamate-gated ion channels that regulate synaptic transmission and modulate neuronal circuits. KARs have strict assembly rules and primarily function as heteromeric receptors in the brain. A longstanding question is how KAR heteromer subunits organize and coordinate...
Autores principales: | Khanra, Nandish, Brown, Patricia MGE, Perozzo, Amanda M, Bowie, Derek, Meyerson, Joel R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997659/ https://www.ncbi.nlm.nih.gov/pubmed/33724189 http://dx.doi.org/10.7554/eLife.66097 |
Ejemplares similares
-
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3
por: Pigoni, Martina, et al.
Publicado: (2020) -
Parkin regulates kainate receptors by interacting with the GluK2 subunit
por: Maraschi, AnnaMaria, et al.
Publicado: (2014) -
Neto auxiliary proteins control both the trafficking and biophysical properties of the kainate receptor GluK1
por: Sheng, Nengyin, et al.
Publicado: (2015) -
Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery
por: Kumari, Jyoti, et al.
Publicado: (2019) -
The Kainate Receptor Subunit GluK2 Interacts With KCC2 to Promote Maturation of Dendritic Spines
por: Kesaf, Sebnem, et al.
Publicado: (2020)