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The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function

The endothelium responds to numerous chemical and mechanical factors in regulating vascular tone, blood pressure, and blood flow. The endothelial volume-regulated anion channel (VRAC) has been proposed to be mechanosensitive and thereby sense fluid flow and hydrostatic pressure to regulate vascular...

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Detalles Bibliográficos
Autores principales: Alghanem, Ahmad F, Abello, Javier, Maurer, Joshua M, Kumar, Ashutosh, Ta, Chau My, Gunasekar, Susheel K, Fatima, Urooj, Kang, Chen, Xie, Litao, Adeola, Oluwaseun, Riker, Megan, Elliot-Hudson, Macaulay, Minerath, Rachel A, Grueter, Chad E, Mullins, Robert F, Stratman, Amber N, Sah, Rajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997661/
https://www.ncbi.nlm.nih.gov/pubmed/33629656
http://dx.doi.org/10.7554/eLife.61313