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The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function
The endothelium responds to numerous chemical and mechanical factors in regulating vascular tone, blood pressure, and blood flow. The endothelial volume-regulated anion channel (VRAC) has been proposed to be mechanosensitive and thereby sense fluid flow and hydrostatic pressure to regulate vascular...
Autores principales: | Alghanem, Ahmad F, Abello, Javier, Maurer, Joshua M, Kumar, Ashutosh, Ta, Chau My, Gunasekar, Susheel K, Fatima, Urooj, Kang, Chen, Xie, Litao, Adeola, Oluwaseun, Riker, Megan, Elliot-Hudson, Macaulay, Minerath, Rachel A, Grueter, Chad E, Mullins, Robert F, Stratman, Amber N, Sah, Rajan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997661/ https://www.ncbi.nlm.nih.gov/pubmed/33629656 http://dx.doi.org/10.7554/eLife.61313 |
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