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Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

To discover new drugs to combat COVID-19, an understanding of the molecular basis of SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of cathepsin L (CTSL) in patients with COVID-19. The circulating level of CTSL was elevated after SARS-CoV-2 infection an...

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Detalles Bibliográficos
Autores principales: Zhao, Miao-Miao, Yang, Wei-Li, Yang, Fang-Yuan, Zhang, Li, Huang, Wei-Jin, Hou, Wei, Fan, Chang-Fa, Jin, Rong-Hua, Feng, Ying-Mei, Wang, You-Chun, Yang, Jin-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997800/
https://www.ncbi.nlm.nih.gov/pubmed/33774649
http://dx.doi.org/10.1038/s41392-021-00558-8