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Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development
To discover new drugs to combat COVID-19, an understanding of the molecular basis of SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of cathepsin L (CTSL) in patients with COVID-19. The circulating level of CTSL was elevated after SARS-CoV-2 infection an...
Autores principales: | Zhao, Miao-Miao, Yang, Wei-Li, Yang, Fang-Yuan, Zhang, Li, Huang, Wei-Jin, Hou, Wei, Fan, Chang-Fa, Jin, Rong-Hua, Feng, Ying-Mei, Wang, You-Chun, Yang, Jin-Kui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997800/ https://www.ncbi.nlm.nih.gov/pubmed/33774649 http://dx.doi.org/10.1038/s41392-021-00558-8 |
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