MIRLET7BHG promotes hepatocellular carcinoma progression by activating hepatic stellate cells through exosomal SMO to trigger Hedgehog pathway

Hepatocellular carcinoma (HCC), commonly caused by liver fibrosis, is a global challenge with high morbidity. Activation of hepatic stellate cells (HSCs) contributes to hepatic fibrosis. Exosomes are small vesicles that play a significant role in cell-to-cell communication. Smoothened (SMO) is the k...

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Detalles Bibliográficos
Autores principales: Xia, Yunhong, Zhen, Lu, Li, Hongxia, Wang, Shuomin, Chen, Sun, Wang, Chongchong, Yang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997896/
https://www.ncbi.nlm.nih.gov/pubmed/33771969
http://dx.doi.org/10.1038/s41419-021-03494-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997896/
https://www.ncbi.nlm.nih.gov/pubmed/33771969
http://dx.doi.org/10.1038/s41419-021-03494-1

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