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MIRLET7BHG promotes hepatocellular carcinoma progression by activating hepatic stellate cells through exosomal SMO to trigger Hedgehog pathway
Hepatocellular carcinoma (HCC), commonly caused by liver fibrosis, is a global challenge with high morbidity. Activation of hepatic stellate cells (HSCs) contributes to hepatic fibrosis. Exosomes are small vesicles that play a significant role in cell-to-cell communication. Smoothened (SMO) is the k...
Autores principales: | Xia, Yunhong, Zhen, Lu, Li, Hongxia, Wang, Shuomin, Chen, Sun, Wang, Chongchong, Yang, Xiaoyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997896/ https://www.ncbi.nlm.nih.gov/pubmed/33771969 http://dx.doi.org/10.1038/s41419-021-03494-1 |
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