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Diquafosol tetrasodium elicits total cholesterol release from rabbit meibomian gland cells via P2Y(2) purinergic receptor signalling

Diquafosol tetrasodium (DQS), a purinergic P2Y(2) receptor agonist, stimulates secretion of both water and mucins from the conjunctiva into tears. Hence, DQS-containing eye drops have been approved as a therapeutic option for dry eye disease in some Asian countries, including Japan. Recent clinical...

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Detalles Bibliográficos
Autores principales: Endo, Ken-ichi, Sakamoto, Asuka, Fujisawa, Koushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997929/
https://www.ncbi.nlm.nih.gov/pubmed/33772064
http://dx.doi.org/10.1038/s41598-021-86433-6