Single-cell analyses of Crohn’s disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions

Crohn’s disease (CD) is a chronic transmural inflammation of intestinal segments caused by dysregulated interaction between microbiome and gut immune system. Here, we profile, via multiple single-cell technologies, T cells purified from the intestinal epithelium and lamina propria (LP) from terminal...

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Detalles Bibliográficos
Autores principales: Jaeger, Natalia, Gamini, Ramya, Cella, Marina, Schettini, Jorge L., Bugatti, Mattia, Zhao, Shanrong, Rosadini, Charles V., Esaulova, Ekaterina, Di Luccia, Blanda, Kinnett, Baylee, Vermi, William, Artyomov, Maxim N., Wynn, Thomas A., Xavier, Ramnik J., Jelinsky, Scott A., Colonna, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997960/
https://www.ncbi.nlm.nih.gov/pubmed/33771991
http://dx.doi.org/10.1038/s41467-021-22164-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997960/
https://www.ncbi.nlm.nih.gov/pubmed/33771991
http://dx.doi.org/10.1038/s41467-021-22164-6

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