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The human intermediate prolactin receptor is a mammary proto-oncogene

The hormone prolactin (PRL) and its receptor (hPRLr) are significantly involved in breast cancer pathogenesis. The intermediate hPRLr (hPRLrI) is an alternatively-spliced isoform, capable of stimulating cellular viability and proliferation. An analogous truncated mouse PRLr (mPRLr) was recently foun...

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Detalles Bibliográficos
Autores principales: Grible, Jacqueline M., Zot, Patricija, Olex, Amy L., Hedrick, Shannon E., Harrell, J. Chuck, Woock, Alicia E., Idowu, Michael O., Clevenger, Charles V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997966/
https://www.ncbi.nlm.nih.gov/pubmed/33772010
http://dx.doi.org/10.1038/s41523-021-00243-7