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The human intermediate prolactin receptor is a mammary proto-oncogene
The hormone prolactin (PRL) and its receptor (hPRLr) are significantly involved in breast cancer pathogenesis. The intermediate hPRLr (hPRLrI) is an alternatively-spliced isoform, capable of stimulating cellular viability and proliferation. An analogous truncated mouse PRLr (mPRLr) was recently foun...
Autores principales: | Grible, Jacqueline M., Zot, Patricija, Olex, Amy L., Hedrick, Shannon E., Harrell, J. Chuck, Woock, Alicia E., Idowu, Michael O., Clevenger, Charles V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997966/ https://www.ncbi.nlm.nih.gov/pubmed/33772010 http://dx.doi.org/10.1038/s41523-021-00243-7 |
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