DNA interstrand cross-links induced by the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine

Oxidative damage to DNA generates 7,8-dihydro-8-oxoguanine (oxoG) and 7,8-dihydro-8-oxoadenine (oxoA) as two major lesions. Despite the comparable prevalence of these lesions, the biological effects of oxoA remain poorly characterized. Here we report the discovery of a class of DNA interstrand cross...

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Detalles Bibliográficos
Autores principales: Rozelle, Aaron L., Cheun, Young, Vilas, Caroline K., Koag, Myong-Chul, Lee, Seongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997976/
https://www.ncbi.nlm.nih.gov/pubmed/33772030
http://dx.doi.org/10.1038/s41467-021-22273-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997976/
https://www.ncbi.nlm.nih.gov/pubmed/33772030
http://dx.doi.org/10.1038/s41467-021-22273-2

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