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DNA interstrand cross-links induced by the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine
Oxidative damage to DNA generates 7,8-dihydro-8-oxoguanine (oxoG) and 7,8-dihydro-8-oxoadenine (oxoA) as two major lesions. Despite the comparable prevalence of these lesions, the biological effects of oxoA remain poorly characterized. Here we report the discovery of a class of DNA interstrand cross...
Autores principales: | Rozelle, Aaron L., Cheun, Young, Vilas, Caroline K., Koag, Myong-Chul, Lee, Seongmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997976/ https://www.ncbi.nlm.nih.gov/pubmed/33772030 http://dx.doi.org/10.1038/s41467-021-22273-2 |
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