Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination

Chronic demyelination in the human CNS is characterized by an inhibitory microenvironment that impairs recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) leading to failed remyelination and axonal atrophy. By network-based transcriptomics, we identified sulfatase 2 (Sulf2) mR...

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Detalles Bibliográficos
Autores principales: Saraswat, Darpan, Shayya, Hani J., Polanco, Jessie J., Tripathi, Ajai, Welliver, R. Ross, Pol, Suyog U., Seidman, Richard A., Broome, Jacqueline E., O’Bara, Melanie A., van Kuppervelt, Toin H., Phillips, Joanna J., Dutta, Ranjan, Sim, Fraser J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998003/
https://www.ncbi.nlm.nih.gov/pubmed/33772011
http://dx.doi.org/10.1038/s41467-021-22263-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998003/
https://www.ncbi.nlm.nih.gov/pubmed/33772011
http://dx.doi.org/10.1038/s41467-021-22263-4

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